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Guerrero Giménez, Martín

Médico, Doctor en Ciencias Biológicas.

 

 

Docente en Facultad de Ciencias Médicas UNCUYO, en el área de Química Biológica.

Actualmente desarrollando actividades en la empresa de investigación clínica, IQVIA, donde administra ensayos clínicos y estudios relacionados con productos, fármacos y procedimientos biotecnológicos y farmacéuticos.

Especializado en Cáncer, Genómica, Epidemiología, Bioestadística y Bioinformática.

Publicaciones de los últimos 5 años

  • Real NE, Castro GN, Darío Cuello-Carrión F, Perinetti C, Röhrich H, Cayado-Gutiérrez N, Guerrero-Gimenez ME, Ciocca DR. “Molecular markers of DNA damage and repair in cervical cancer patients treated with cisplatin neoadjuvant chemotherapy: an exploratory study.”, Cell Stress and Chaperones, 2017, DOI: 10.1007/s12192-017-0811-z
  • Gómez LC, Sottile ML, Guerrero-Gimenez ME, Zoppino FCM, Redondo AL, Gago FE, Orozco JI, Tello OM, Roqué M, Nadin SB, Marzese DM, Vargas-Roig LM. “TP73 DNA methylation and upregulation of deltaNp73 are associated with an adverse prognosis in breast cancer”. Journal of clinical pathology. BMJ PUBLISHING GROUP. 2017, DOI: 10.1136/jclinpath-2017-204499
  • Maniero Ávila M, Guerrero-Gimenez ME. Fanelli MA, Wuilloud RG. “Inorganic mercury in mammary cells: viability, metal uptake but efflux?”. BIOMETALS. Berlin: SPRINGER. 2017 vol. n°. p - . DOI: 10.1007/s10534-017-0068-0.
  • Trafimow D, Amrhein V and other 52 authors including Guerrero-Gimenez ME. “Manipulating the alpha level cannot cure significance”. Frontiers in Psychology, 2018, DOI: 10.3389/fpsyg.2018.00699.
  • Zoppino FCM*, Guerrero-Gimenez ME*, Castro GN, Ciocca DR. “Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer”. BMC Cancer, 2018, DOI: 10.1186/s12885-018-4621-1. * Zoppino y Guerrero-Gimenez comparten la primer autoría.
  • Lang BJ, Guerrero-Giménez ME, Prince TL, Ackerman A, Bonorino C, Calderwood SK.” Heat Shock Proteins Are Essential Components in Transformation and Tumor Progression: Cancer Cell Intrinsic Pathways and Beyond”. Int J Mol Sci. 2019 Sep 11;20(18). pii: E4507. doi: 10.3390/ijms20184507. Review.
  • Sasso CV, Santiano FE, Campo Verde Arboccó F, Zyla LE, Semino SN, Guerrero-Gimenez ME, Pistone Creydt V, López Fontana CM, Carón RW. “Estradiol and progesterone regulate proliferation and apoptosis in colon cancer”. Endocr Connect. 2019 Mar 1;8(3):217-229. doi: 10.1530/EC-18-0374.
  • Prince TL, Lang BJ, Guerrero-Gimenez ME, Fernandez-Muñoz JM, Ackerman A, Calderwood SK. “HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity”. Cells. 2020 Apr 22;9(4):1046. doi: 10.3390/cells9041046. Review.
  • Guerrero-Gimenez ME, Fernandez-Muñoz JM, Lang BJ, Holton KM, Ciocca DR, Catania CA, Zoppino FCM. Galgo: a bi-objective evolutionary meta-heuristic identifies robust transcriptomic classifiers associated with patient outcome across multiple cancer types. Bioinformatics. 2020 Dec 22;36(20):5037-5044. doi: 10.1093/bioinformatics/btaa619. PMID: 32638009.
  • Pennacchiotti G, Valdés-Gutiérrez F, González-Arriagada WA, Montes HF, Parra JMR, Guida VA, Gómez SE, Guerrero-Gimenez ME, Fernandez-Muñoz JM, Zoppino FCM, Carón RW, Ezquer ME, Fernández-Ramires R, Bruna FA. SPINK7 expression changes accompanied by HER2, P53 and RB1 can be relevant in predicting oral squamous cell carcinoma at a molecular level. Sci Rep. 2021 Mar 25;11(1):6939. doi: 10.1038/s41598-021-86208-z. PMID: 33767253; PMCID: PMC7994578.
  • López Fontana G, Rey L, Santiano F, López Fontana R, López Laur JD, Zyla L, Valdemoros P, Guerrero-Giménez ME, Fernández-Muñoz JM, Gómez S, Bruna F, Guglielmi JM, Carón R, López Fontana C. Changes in prolactin receptor location in prostate tumors. Arch Esp Urol. 2021 May;74(4):419-426. English, Spanish. PMID: 33942735.
  • Lang BJ, Guerrero-Gimenez ME, Prince TL, Okusha Y, Bonorino C, Calderwood SK. The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response. Arch Toxicol. 2021 Jun;95(6):1943-1970. doi: 10.1007/s00204-021-03070-8. Epub 2021 May 18. PMID: 34003342. Review
  • Nolly MB, Vargas LA, Correa MV, Lofeudo JM, Pinilla AO, Rueda JOV, Guerrero-Gimenez ME, Swenson ER, Damiani MT, Alvarez BV. Carbonic anhydrase IX and hypoxia-inducible factor 1 attenuate cardiac dysfunction after myocardial infarction. Pflugers Arch. 2021 Aug;473(8):1273-1285. doi: 10.1007/s00424-021-02592-5. Epub 2021 Jul 6. PMID: 34231059

Colaboraciones

  • Laboratorio de Radiología Oncológica - Beth Israel Deaconess Medical Center - Universidad de Harvard
  • Laboratorio de Sistemas Inteligentes - Facultad de Ingeniería - Universidad Nacional de Cuyo
  • Instituto de Medicina y Biología Experimental de Cuyo